{"product_id":"fypryst-combo-cat-spot-on-fleas-ticks","title":"Fypryst Combo Spot-on to prevent fleas, ticks, lice 50 mg\/60 mg N1","description":"\u003cp\u003eFypryst Combo Spot-on to prevent fleas, ticks, lice 50 mg\/60 mg N1\u003c\/p\u003e\n\u003cp\u003eMeans against fleas, ticks for cats and domestic ferrets - Fypryst combo cat and ferret, 50\/60 mg 1 pip., non-prescription vet. medicine - reg. NO - VA - 089588\/1\u003cbr\u003e\u003cbr\u003eNAME OF THE VETERINARY MEDICINE\u003cbr\u003eFypryst Combo 50 mg\/60 mg solution for instillation on the skin of cats and domestic ferrets.\u003cbr\u003e\u003cbr\u003eQUALITATIVE AND QUANTITATIVE COMPOSITION\u003cbr\u003e\u003cbr\u003eOne 0.5 ml pipette contains:\u003cbr\u003e\u003cbr\u003eActive substances:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFipronil 50 mg;\u003c\/li\u003e\n\u003cli\u003eS-methoprene 60 mg.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003eExcipients:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eButylhydroxyanisole (E320) 0.1 mg;\u003c\/li\u003e\n\u003cli\u003eButylhydroxytoluene (E321) 0.05 mg;\u003c\/li\u003e\n\u003cli\u003ePovidone (K25);\u003c\/li\u003e\n\u003cli\u003ePolysorbate 80;\u003c\/li\u003e\n\u003cli\u003eEthyl alcohol 96%;\u003c\/li\u003e\n\u003cli\u003eDiethylene glycol monoethyl ether.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePHARMACEUTICAL FORM\u003cbr\u003eSolution for instillation on the skin.\u003cbr\u003eClear, yellow solution.\u003cbr\u003e\u003cbr\u003eTARGET SPECIES\u003cbr\u003eCats, domestic ferrets.\u003cbr\u003e\u003cbr\u003eINDICATIONS\u003cbr\u003e\u003cbr\u003eFor cats:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor the prevention of flea infestations and mixed infestations of fleas and ticks and\/or lice:\u003c\/li\u003e\n\u003cli\u003eFor the treatment of flea (Ctenocephalides spp.) infestation. The effect of the insecticide against the infestation of young adult fleas remains for 8 weeks. For the prevention of flea reproduction by inhibiting the development of eggs (ovicidal action), larvae and pupae (larvicidal action) from eggs laid by adult fleas, 8 weeks after application.\u003c\/li\u003e\n\u003cli\u003eFor the treatment of tick (Ixodes ricinus, Dermacentor variablis, Dermacentor reticulatus, Rhipicephalus sanguineus) infestation. The acaricidal effect of this drug against ticks remains for 4 weeks.\u003c\/li\u003e\n\u003cli\u003eFor the destruction of lice (Felicola subrostratus).\u003c\/li\u003e\n\u003cli\u003eThis veterinary medicine can be used as part of a treatment strategy for flea allergy dermatitis if it has been previously diagnosed by a veterinarian.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eDomestic ferrets:\u003cbr\u003eUsed to prevent fleas and mixed flea and tick infestations:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFor killing fleas (Ctenocephalides spp.). The effect of the insecticide against the infestation of young adult fleas remains for 4 weeks. For the prevention of flea reproduction by inhibiting the development of eggs (ovicidal action), larvae and pupae (larvicidal action) from eggs laid by adult fleas.\u003c\/li\u003e\n\u003cli\u003eFor the destruction of ticks (Ixodes ricinus). The veterinary medicinal product has a persistent 4-week acaricidal effect against ticks (based on experimental data).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCONTRAINDICATIONS\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eDue to lack of data, do not use in kittens under 8 weeks of age and\/or kittens weighing less than 1 kg. Do not use veterinary medicines for domestic ferrets under 6 months of age.\u003c\/li\u003e\n\u003cli\u003eDo not use in sick animals (systemic diseases, fever, etc.) and animals in the recovery period.\u003c\/li\u003e\n\u003cli\u003eDo not use in rabbits, as side effects and even death are possible.\u003c\/li\u003e\n\u003cli\u003eIn the absence of studies, the use of this medicinal product is not recommended in animals other than the target species.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSPECIAL PRECAUTIONS FOR USE\u003cbr\u003eSpecial precautions for use in animals:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAvoid getting the medicine into the animal's eyes.\u003c\/li\u003e\n\u003cli\u003eIt is important to make sure that the medicine is applied in a place where the animals cannot lick it and to ensure that the animals do not lick each other after treatment.\u003c\/li\u003e\n\u003cli\u003eIndividual ticks may be absorbed. For this reason, the risk of transmission of infectious diseases cannot be completely excluded under adverse conditions.\u003c\/li\u003e\n\u003cli\u003eThe potential toxicity of this veterinary medicinal product is unknown in cats less than 8 weeks of age living with the mother to whom the medicinal product has been administered. In this case, take special care.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSpecial precautions to be taken by a person using veterinary medicinal products for the treatment of animals:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThis medicine can cause irritation of the mucous membrane, skin and eyes, so avoid contact of the medicine with the mucous membrane of the mouth, skin and eyes.\u003c\/li\u003e\n\u003cli\u003ePersons with known hypersensitivity to insecticides or alcohol should avoid contact with this veterinary medicinal product. Be careful not to let the medicine come into contact with the skin. If this has happened, wash your hands with soap and water.\u003c\/li\u003e\n\u003cli\u003eIf the medicine accidentally gets into the eyes, rinse the eyes thoroughly with clean water.\u003c\/li\u003e\n\u003cli\u003eWash hands after use.\u003c\/li\u003e\n\u003cli\u003eDo not smoke, drink or eat during treatment.\u003c\/li\u003e\n\u003cli\u003eTreated animals should not be petted until the application site is dry, and children should not be allowed to play with freshly treated animals. For this reason, it is recommended to treat animals not during the day, but early in the evening, and not to allow recently treated animals to sleep with their owners, especially children.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003ePOSSIBLE SIDE EFFECTS\u003cbr\u003e\u003cbr\u003eAmong the very rare (less than 1 animal in 10,000 animals treated, including individual reports) possible side effects reported after use are transient skin reactions at the application site (scaling, local alopecia, pruritus, erythema) and generalized pruritus or hair loss. Increased salivation, reversible neurological symptoms (increased sensitivity, depression, nervous symptoms) or vomiting have also been observed after taking the drug.\u003cbr\u003eIn case of licking the application site, temporary increased salivation may be observed mainly due to the properties of the carrier.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eUSE DURING PREGNANCY, LACTATION OR LAYING\u003cbr\u003e\u003cbr\u003eFor cats:\u003cbr\u003eThe medicine can be used during pregnancy.\u003c\/p\u003e\n\u003cp\u003eDomestic ferrets:\u003cbr\u003eThe safety of these veterinary medicinal products for domestic ferrets during pregnancy and lactation has not been established. Use only after a benefit-risk assessment by the attending veterinarian.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eINTERACTIONS WITH OTHER DRUGS AND OTHER TYPES OF INTERACTIONS\u003cbr\u003eNot known.\u003cbr\u003e\u003cbr\u003eDOSAGE AND METHOD OF ADMINISTRATION\u003cbr\u003eDosage:\u003cbr\u003e\u003cbr\u003eThe content of one pipette is 0.5 ml, which corresponds to 5 mg\/kg fipronil and 6 mg\/kg (S)-methoprene, for application to the skin of a cat (instillation).\u003cbr\u003eDue to the lack of drug safety studies, the minimum interval between applications is 4 weeks.\u003cbr\u003eOne pipette contains 0.5 ml, which corresponds to 50 mg of fipronil and 60 mg of (S)-methoprene, for application to the skin of a domestic ferret (instillation).\u003cbr\u003eThe minimum interval of use is 4 weeks.\u003c\/p\u003e\n\u003cp\u003eMethod of use:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eRemove the pipette from the package. Hold the pipette vertically with the cap upwards, unscrew and remove the cap.\u003c\/li\u003e\n\u003cli\u003eTurn the cap upside down and put the other end back on the pipette. Press and twist the cap to break the seal and then remove the cap from the pipette.\u003c\/li\u003e\n\u003cli\u003eApply to the skin at the base of the neck in front of the shoulder blades.\u003c\/li\u003e\n\u003cli\u003ePart the hair so that the skin is visible. Place the tip of the pipette on the skin and squeeze the single-dose pipette several times to empty the contents directly onto the skin at one point.\u003c\/li\u003e\n\u003cli\u003eTransient changes in the coat (sticky\/greasy coat) may appear at the site of application.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eOVERDOSE\u003cbr\u003eThe risk of side effects increases with an overdose.\u003cbr\u003e\u003cbr\u003eFor cats:\u003cbr\u003eIn laboratory safety studies, no side effects were observed in cats 8 weeks of age and older, as well as in cats weighing approximately 1 kg, when administered once a month at five times the recommended dose for 6 consecutive months.\u003cbr\u003eItching may be observed after application. If you apply too much solution in one place, you may notice hair clumping at the application site. If this happens, the clumping will disappear within 24 hours of application.\u003c\/p\u003e\n\u003cp\u003eDomestic ferrets:\u003cbr\u003eIn domestic ferrets 6 months of age and older, given once every two weeks four times at five times the recommended dose, weight loss has been observed in some animals.\u003cbr\u003ePHARMACOLOGICAL PROPERTIES\u003cbr\u003e\u003cbr\u003ePharmacotherapeutic group: means against ectoparasites for external use, including insecticides.\u003cbr\u003e\u003cbr\u003ePharmacodynamic properties:\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eFipronil is an insecticide and acaricide belonging to the phenylpyrazole group. It interacts with ligand-gated chloride channels, especially those regulated by the neurotransmitter gamma-aminobutyric acid (GASS), thereby blocking the pre- and postsynaptic transfer of chloride ions across cell membranes. It causes uncontrolled central nervous system activity and death in insects and mites. Fipronil kills fleas within 24 hours, ticks (Dermacentor variablis, Dermacentor reticulatus, Rhipicephalus sanguineus, Ixodes ricinus) and lice 48 hours after application.\u003c\/li\u003e\n\u003cli\u003e(S)-Methoprene is an insect growth regulator (IAR), from a class of compounds known as juvenile hormone analogues, which arrest the development of insects at one stage of development. This substance acts similar to juvenile hormones and causes impaired development and death of fleas at all stages of their development. The ovicidal effect of (S)-methoprene on the animal occurs either by direct penetration into newly laid eggs or by penetration through the cuticle into the body of an adult flea. (S)-methoprene effectively stops the further development of flea eggs and larvae, which protects against contamination of the immediate surroundings of animals with fleas in various stages of their development.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFypryst Combo Spot-on to prevent fleas, ticks, lice 50 mg\/60 mg N1\u003c\/p\u003e","brand":"KRKA","offers":[{"title":"Default Title","offer_id":46902985982277,"sku":"4013-1","price":10.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0552\/4327\/6372\/files\/lidzeklis-pret-blusam-ercem-kakiem-un-majas-seskiem-fypryst-combo-cat-and-ferret-50-60-mg-1-pip-bezrecepsu-vet-zales-reg-nr-va-072463-3-original_0e326ef7-c861-4140-9d41-4634d1dd9d7a.jpg?v=1695220466","url":"https:\/\/zuzu.land\/en-ca\/products\/fypryst-combo-cat-spot-on-fleas-ticks","provider":"ZuZu.land","version":"1.0","type":"link"}